A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes
نویسندگان
چکیده
منابع مشابه
A two-locus gene conversion model with selection and its application to the human RHCE and RHD genes.
A two-locus gene conversion model with selection is developed. Under the joint action of selection, mutation, gene conversion, recombination, and random genetic drift, approximate formulas for the expectations of the moments of allele frequencies and the expected amounts of variation within and between two loci are obtained by a diffusion method assuming relatively strong selection. It is shown...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2003
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1031592100